Oh, you're an AP champ?
Well, you have dramatically lower damage, next to no sustain, less utility items, and can only build one stat to be useful.
Meanwhile, AD champs have a fucking mountain of items to choose from, have more sustain than any champion in the game ever had (thanks Lifesteal!), can one shot you, can build on-hit and tank and still one shot you, can build offtank AD and still one shot you, can build crit and AS and one shot you, can build one damage item into full tank and still one shot you, don't have to aim to do damage and can just click on you and go AFK, have SEVERAL items to avoid CC or remove it, have several items to prevent them from dying, have no resource or cost or drawback in their autos, no significant CDs on their main form of damage...
Yet, those braindead AD champs are the strongest in the game, hands down.
I can really tell that Riot is ABSOLUTELY not biased towards AD at all!
(She has too much damage though)

.. maybe it;s just the pick rate


sustain.
mana sustain/ utility.
utility

Better health regen than a lifestealing Vayne.
One shot a Jhin with a Q late game
One of the two biggest hypercarries.
A godly hypercarry comparable to the likes of Azir or Kayle