When are you going to nerf Brand/Lux?
Having "skillshots" that aren't even hard to land is not an excuse to instantly kill anybody touched by them.
Brand (especially in the bot lane) does far too much damage at all stages of the game. He needs to lose one of the parts of his passive. Doing a %max hp DoT and doing a burst of it as well is just stupid for someone who can AoE a team down on his own. What exactly did you want brand to be? A lane bully? A teamfight god? An assassin? I get he's immobile and should have a trade off for that but what you've given him is just far too much burst. Comparing him to someone similar would be veigar who typically if he lands his stun you usually get in free trades or a free kill. He has a very long window of opportunity to jump on (even when he's under tower) to bully when that stun is down. Brand does not have that opportunity in the bot lane and in mid lane it's insanely hard to punish due to brands retarded burst.
(I'll admit i'm a bit salty about my last game not so much about losing it but because despite being able to tank 4 people and live with a little over half an hp bar as sion I somehow was at 25% hp after taking 3 hits for brand that's just ridiculous that he's out damaging 4 people combined on his own and they had freaking OP champs ((rengar, syndra, kha,ezreal))
Lux is another person on this case. She lands a Q and boom dead. Yes, she's immobile and "skill(hah as if) shot" based. That's NOT an excuse to make them broken in every area you wanted them to be good in. With her double shield, aoe slow and double snare all on massively low CD's punishing her for missing a skillshot is nearly impossible unless they're just flat out stupid and run into melee range.
There is no way you found malzahar and Zyra an issue but you aren't touching brand or lux who are far worse. Malz was only dumb cause of his stupid new passive which could've easily been reverted and Zyra just needed her numbers fixed without hurting mid too much. These two on the other hand have far too much utility and damage with little to no drop back