Can most mana hungry champs see a base mana regen buff because of the lack of items that give it?
Such as 

because
and
(in
's case) were necessary for these champs to just be able to poke / farm during laning phase and not instantly become oom.
And let's not forget the champs with the most mana issues in the early - mid game:
and 
850 gold
450 gold
125 gold