I thought it was amusing (e.g. Draven-
is a riot), but yes, after the first game or two it gets really old. Also makes it quite hard to differentiate champions in teamfights; the game is less playable overall.
I don't think keeping this until the end of the weekend is a good idea. One day might be fine. But even then, I wish it were a toggle, so I can be amused for a couple of games before turning it off.
Also have to say that doing this right alongside the release of several new skins was probably a bad idea. I've got Meowkai, but can't even see his precious face outside of draft. Maybe if this sort of thing is done in the future, exclude new skins from the Dravenization?
In short: I laughed, but in the future, please let us opt out at some point. The joke is rather short-lived, after all!