I honestly beg to differ.
The biggest problem with that is that stats are virtually Flatlined in that game mode. You don't really snowball in that game mode like you would in SR. And playing a glass cannon will leave you vulnerable to ambushes, which is very possible in a game mode without tons of vision.
Personally, I put my monery on Juggernauts, specifically AA based Juggernauts like Udyr, Olaf, and Volibear. Being AA focus gives you a fair amount of Single target DPS, giving dueling power against any opponent you come across. That dueling power also helps you take Xerath and Ascend. And the last thing of Note, Wormargs. If you build Wormargs with enough HP, you will have all the sustain you need. This is particularly annoying if said Juggernaut with Wormargs get's ascended, because if you can't kill him in one go, he will recover.