My prediction for S6 meta.

Waveclear champions and splitpushers are going to be very strong, in response to this Quinn is going to become one of the top marksmen. after that, I expect some very specific anti-carry and dueling splitpushers to become even more popular. Fiora definitely, maybe udyr/jax/nasus. Singed will probably be up there again due to the sheer speed at which he pushes lanes, malzahar and heimerdinger will probably end up being played quite a lot. Quinn may end up being played mid a lot to take advantage of her insane roaming power to both take over the earlygame and quickly deal with splitpushers later in the laning phase.

Champions like Lee Sin will probably end up being even MORE popular since it takes so long for everybody else to get their jungle item now.