Hi,
Jungle Karma has existed between the Karma mains for a while, and she has always been able to clear the jungle. The new addition to her W being able to tether to monsters allows her to sustain more easily.
For build, I would recommend using the same build as Nidalee and some Diana's (Magus into ROA). Health is an awesome stat on Karma.
Your runes look fine. I like to use AS reds.
For starting abilities, you have a variety of options. If you are going to get a good leash, you can start E and simply auto and smite Gromp. The next skill is up to you. W allows you to sustain better, but Q is better for clearing faster. Essentially, Q is better for a quick clear (Gromp, Blue, Wolves then back for Rangers). W is better for a whole clear, as you can easily sustain yourself off of the Blue Buff. Find the ability sequence that works for you and you can stick with it. As far as I can tell, both are viable and it comes down to the situation and your preference.
Ganks should be a breeze. If you are half health, you can still gank, as you can just RW the enemy laner. If you are full, use RQ. You won't get many kills in the early game normally - this is totally okay! Karma jungle is extremely supportive and relies on snowballing other lanes to victory. Playing her with a hypercarry on the team is extremely effective.
Some practice with it and you'll be clearing no problem.
BTW: Karma jungle has actually been played in the LCS before :)
Hope I helped,
Karma Main
