Whether it has the least amount of text, has the most simple of effects, least amount of interaction in kit or other wise, or any other reason you can think of off the top of your head.
I'll start with Teemo's Blinding dart. Very short text, simple execution with point and click, only does damage and blinds, a binary and easy to understand effect.
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Akali Crescent Slash. REALLY short text, simple execution by pressing a button, only does damage and doesn't proc her Q. You spin and deal damage around you, no more no less.
's Drain. You steal their health.
W: Heal + Remove crowd control
rek'sai q, aoe auto attacks
Rightclick. You slap them with your weapon. Or fists.
Syndra q: Place a ball to do damage
Annie's Q. Boring, point and click fireball. Woo.
R
Health for everyone!
Veigar's primordial burst is pretty simple: press R, get kill.
Pantheon Q: spear shot.
Throw a spear. Can't miss.
teemos blinding dart is very complex because the blinding mechanic by itself is very complex. i think the simplest ability in the game is pantheons Q, it costs some mana and deals some damage, literally cant make it simpler.
