New Runes Have Almost Invalidated Melees
I am a melee kind of guy. I main Nasus, Shen for the most part but also like to pick up Warwick, Galio, Maokai, Zac and Nautilus as well.
What kills me though is how Riot decided to give us almost no defensive stats early but there are a ton of abusive combos with some Runes and Champions kits especially if they are ranged and can proc dot damage. Even hyper aggressive melee's that have high kill pressure at lvl 1-3 are abusing things like Summon Aery, Press the Attack and Lethal Tempo.
Teemo with Summon Aery is stupidly oppressive as his poison tic from his AA's can trigger the damage multiple times. Riven and Pantheon can also make strong use of this Keystone to give them more burst and kill pressure than ever before.
Vayne with Lethal Tempo is absolutely the stuff of nightmares. She can basically auto proc her passive in 1 second late game and melt a tank in about 2 or 3 tops.
Corki with Press the Attack is absolutely insane. With his Gatling gun running he can basically invalidate any champions health in a matter of seconds. Once he get's Triforce he is nigh impossible to kill without dying yourself. Urgot is another one. Being medium range you can stay out of harms way but one mistake and he gets the flip could, most likely will, be your death at level 3.
These are just examples and I know there are other heavy abuse cases but I just want Riot to give us some decent defenses to either take or they need to start evaluating the base stats of all there struggling melee's who are absolutely getting slaughtered by the insane amount of damage that is now in the game.
I will admit that the effective health on tanks through shields or damage reduction passives helps them weather this better than other melee's but the ranged match ups are hell. Especially Teemo, Vayne and Heimdinger who can basically attack you consistently with little to no opportunity to outplay or challenge them.