My biggest concern about the rune update.

Is that champions that rely on very unusual and specific runes are going to get left in the dust. For example, nearly every Kayle player runs 20% scaling CDR because it's the only efficient way to get 40% cdr on her since no CDR items other than Nashors are particularly good on her. AS based junglers like Shyvana and Yi are also reliant on 29% AS from runes to clear the early jungle at a reasonable pace.