Its really interesting seeing which champs have risen to the top with the changes
http://na.op.gg/statistics/champion/
Top 10 winrates for the day (at the time of this post):
#1: 
#2: 
#3: 
#4: 
#5: 
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#8: 
#9: 
#10: 
They seems to be a few poke mage along with a bunch of splitpushers. Even looks like Tri is finding its way into Shyv's buildpath for splitpushing. Heimer has always been great at splitting. Yorick and Udyr are both Tri users and great for splitting. Teemo pretty self explanatory. I expected to see a lot of them running Demolish, but after checking it seems Yorick is the only one out of those who runs it regularly.
Then we have a few poke mages. Xerath is near the top and althoough Ziggs didnt make the top 10, he's still doing pretty well himself. Curious as to why other poke mages like Lux arent doing so hot.
Kog shouldn't be much of a surprise considering all the on-hit damage synchronizing with Lethal Tempo. I thought I would see Vayne doing really well because of this too, but she's only sitting on a 50.8% WR.
I really have no theory on Rammus and Taric. Theres a bunch of %resistances and %HP gains in the new runes which woud work quite well for them. Also explains why Malphite is sitting at #11
Just some brief observations. Obviously not a ton of data to work with yet, but I wanted to share what I've noticed at least so far