Now that all three of Ryze's basic abilities are single target, and have low AP scalings and CD's, would Muramana into tank items (likely getting an early Frozen Heart) be a viable build? As I see it,
Pros: Hybrid damage Likely the highest damage single offensive item build Ryze has (Seraph's Embrace might beat it) Tankier than standard Ryze builds
Cons: Hybrid damage Lower damage than standard Ryze Pretty bad until Muramana Burns through mana very quickly
DarkLordArbitur2 votesok so from a D2 friend of mine who mains ryze:
(not in this order) is the dream build on ryze, because you go through all his rotations, proc all that damage from muramana, have 5k mana, have a shit ton of AP, and after all that, theres about a second where you can do an autoattack and deal a shit ton more damage with spellblade+muramana+you have 5k mana so shit ton of AD.
Marshbouy1 votesor you could just build seraphs?
CerealBoxOfDoom1 votesor you could just build seraphs?
seraphs wont trigger the bonus damage rapidly for tons of bonus damage
Elite4Runner1 votesInteresting.
AD per mana
Mana, armor, CDR
(Strong recommendation)
Mana, armro CDR (caps CDR) Spellblade
(Possibly strong)
Health, +25% base AD, Passive (+50% base AD and shield when active), (Works well with sheen passive)
(Possibly strong)
Health, Mana, Eternity passive (consuming mana helps to restore health, absorbing damage helps to restore mana, which also works to increase effectiveness of 's active)
I feel this is so far missing MR, but there are no items that give MR and Mana. Maybe just getting 
, or going more offensive with 
or 
....
Either way, worth looking into.
SteelMankind1 votesNot sure if you'd ever have time to autoattack with Ryze, so the Steraks and Iceborn don't make much sense.
Elite4Runner1 votesNot sure if you'd ever have time to autoattack with Ryze, so the Steraks and Iceborn don't make much sense.
Ah, I see what you're getting at. I was confused because I had forgot that Muramana's active applies on single target abilities as well. I would still really consider keeping Iceborn because it does give one of the highest amounts of mana, a decent amount of armor and 20% CDR, but I can agree that Sterak's is a little out of place. Although the health and shield still sound good to me, and if you ever do manage to sneak an auto attack in, it would hurt a bit more. ... Plus it's a pretty cheap item.
Are you wanting to avoid AP?
SteelMankind1 votesInsofar as to be as tanky as possible with a single damage item - if it wasn't for the fact that MS Quints are good on Ryze, I would take AP Quints. Kinda like how when tank Ekko was a thing, he wouldn't get much AP despite having good ratios.
Elite4Runner1 votesThe downside of this though is that I don't see this being any stronger in general than any other 'AD blue build' unless you have some AP to give additional mana from his passive.
SteelMankind1 votesIt's worth considering because you can spam spells faster than you can autoattack, even with 2.5 attack speed. Due to Ryze's Q refreshing with W and E, QEQWQ can be done very quickly and will apply Muramana 5 times, if you have it.
BluePolarizer1 votesWhy not just go modified version of old s4 Ryze but with Muramana instead of Seraphs?
SteelMankind1 votesBecause I'm fairly certain that Seraph's > Muramana on Ryze once you allow yourself to get multiple offensive items.
BluePolarizer1 voteshave you done the math?