Most Zac players will engage with E from more or less as far as they can to avoid the chance of detection.
Deep wards and wards over walls (for instance, the wall looping around to river on red side bottom lane) help tremendously.
Also you are incorrect.
If he builds tank, he has almost no damage.
If he builds AP, he's so squishy it doesn't matter.
His resurrection passive is fairly long, and you can see if it's up or not by clicking on him. Also if you get his resurrection passive down, it's essentially a kill because he will now have to play safer. Also tower will focus his blobs under towers, meaning tower dives are very risky unless you're low enough it wouldn't matter if he was Zac or anyone else.
And warding the unconventional places he'd gank from helps a great deal.
Also, as with any sustain tank, Exec's Call/Last Whisper/Mortal Reminder help.