Probably the cheesiest strategy that is extremely hard to beat
Just played against this and I have to admit, it is absolutely disgusting. But I'm pretty sure it wouldn't work against any team with coordination.
A combination of Kog'Maw and Lulu bot lane. Lulu builds early CDR and high AP, while Kog'Maw takes
with
and other on-hit items. All these two did after Kog got the red smite with bloodrazer was sit in a brush that they pinked, Kog would E+Q+W while Lulu would use E and W while having
, and with the insane amount of attack speed and on-hit effects there were, it melted just about anyone hit within a few seconds. As a note, one of my deaths had a 0.7 second time on it according to the death timer. And I saw Sejuani go to the brush, ward it, see them, and die while she tried to dash away. Granted, things probably would have worked better for us if Sejuani built MR and HP rather than AP. But in all honesty, I feel like that combination is way too powerful and with the damage it deals, I'd be scared as hell to see what would have happened if Kog got either
or
.
Also, it seems like the people who did this in the game have been doing this for a large number of games and are now on a massive win streak because of it.