Neeko's E is extremely not okay. Who let this make it into the game?
The speed boost and size increase from hitting two minions actually makes it so fast that it's impossible to sidestep it when aimed directly at you, even with boots 2.
This is 'acceptable' on certain skill shots, but virtually every skill shot with speed like this (i.e. Zoe's bubble) has a wind up that warns you it's being casting, giving you time to start moving before it comes out. However, her E is an instant cast and doesn't have any sort of wind up; if it's aimed directly at you, you need to use a dash or flash to dodge it.
Laning against this monstrosity as an immobile champion is completely insane. This ability should not have been released like this.