As a nasus player I completely agree
Vayne is my most hated ADC. with Ashe pretty far up on the list because once she gets her momentum going to kite me, there is almost nothing I can do if I don’t have flash up.
Oh and laning against a Quinn with electrocute and ignite is hell. I played both parts of the matchup, both as nasus and as Quinn and the nasus get absolutely fucked almost every time.
Most people don’t understand that all you really need to do to negate nasus is a tank buster. Vayne is the most effective, and Shyvana is one of my personal favorites.
Shyvana has good poke when maxing e and it deals a shit ton of damage at lvl 6 in dragon form. I do a semi weird build on shyvana where I max e for the powerspike at lvl 6, but I go PTA, rush titanic and usually get rageblade after to transition to on-hit Shyvana. This build was better tho before Riot changed rageblade to give armor pen and magic pen.