In the resolve tree you have health regen or Summ CD: How is that even a question?

15% CD reduction on your summoners is an unbelievable winner in at least 99% of cases in the far right tanky mastery tree. In the far left tree Vampirism beats Natural Talent basically every time.

This is why I liked the old mastery tree better, you could mix and match any points you wanted to be effective towards your playstyle but now you just make decisions that aren't really decisions at all.