Dumb Full Lethality Builds on Bruisers are Fun.
So recently I ran a full lethality rune page, precision and all 3 lethality items on Garen and Wuk, combined with a Black Cleaver for extra Pen. You deal sooooooo much damage! Who said that it's only good on assassins.
You'd think that their squishies would at least go and build a chain west but nope. They just remain stubborn and you have a great time dealing true damage to them.
Here are some that I want to try besides Wukong and Garen ( both of which have worked greatly btw ).

I'd usually go for something like
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and 10% CDR scaling in glyphs to max out CDR. Maybe a Triforce on Vi instead of a Black Cleaver and something other than a Dead Man's on Urgot.
Some other champions that aren't as bruiserish but aren't assassins either which I think a lethality build could be fun on:
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You already know it on this guy but I thought why not just ignore crit completely and go for full Lethality Duskblade Passive true damage Parrrleys and barrels for some extra fun.

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One-shotting love taps and absolutely devastating ultimates. Yet again, who needs crit when you can have this instead.

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Imagine this: Ezreal's Q plus a ton of AD plus duskblade's 250 true damage, plus sheen plus 80 lethality plus 50% armor penetration plus potential 15% extra damage from Dominik's - every few seconds or so. Enjoy:

Lots of fun, suprisingly non-troll and a great way to teach those squishy mage and adc players to actually buy armor. I would encourage you to try these, especially the last 3 I mentioned because I'm shit on those champs and you can test it for me instead and tell me afterwards. Doesn't seem to be limited to AD assassins after all it seems like.