lets be honest here, the game isnt going to change that much.
i hate to kill hype, but as someone who played with the new runes on PBE, the main difference that i felt is alot of champions, particularly bully champions, got weaker because of less raw stats. aside from that not much changed in regards to how the game is played. there will be some new champ specific strategies for sure, but games will still be league. fights will still be fast and chaotic, games in higher elo will still be shorter than average, games in lower elo will still be longer than average, and bot lane will still be the most dominate lane in the game.
the game wont change nearly as drastically as some people think and hope it will. you will get cute niche champ strategies like full tank sion shitting on turrets, but thats about it.