To be honest I have thought before about how they could rework Warwick. His lore is pretty cool, but still stereotypical evil genius trying to do something he shouldn't (Frankenstein), the thing that really bothers me about him though is his limited this-is-your-combo kit. He literally can press R, Q, and then start to auto attack things. It would be cool if his abilities when reworked could be used in a plethora of ways, that allow him and his enemies to have more diverse gameplay.
By the way, concerning the whole bot laner thing you brought up, they could possibly make him a marksman transformation champion. It would fit lore-wise since he was adept at hunting things before transforming into a werewolf. Perhaps his ultimate could transform him into a werewolf and his normal form would consist of trap-setting and utility used to hunt down enemies.