Something I've noticed that is SLIGHTLY unfair: Some Champions have "out-of-combat" cooldowns
By this, I mean that some of their abilities have a countdown/cooldown that, upon ending, shows them that they're considered "out of combat".
To picture this, look at Taliyah's passive when she enters combat; it starts counting down until Rock Surfing can be used again. The same can be seen on Rengar; once that countdown on his passive ends, he's out of combat and starts to lose Ferocity.
Some Champions don't get this countdown, though, something which can mess with your intuition on when certain effects will become active (i.e. out-of-combat movement speed, Ocean Drake regen, etc). It might not sound like much, but at the very least it's a QoL annoyance.
To address this, I think there needs to be a gemstone (of sorts) on your HUD that changes color depending on when you're in or out of combat, or perhaps it fills up with a color over time, counting you as out-of-combat once it's full. I got the idea from Might and Magic 6: The Mandate of Heaven, though it works differently in that (more like a proximity sensor).
This sort of thing wouldn't be REQUIRED, but it'd help out in terms of making things fair for everyone.