Brand mid really can't do much of anything against a competent opponent. He's much more annoying as a support, but in mid he's incredibly hard to pull off right.
Orianna has no early game. Her entire strength comes from late game teamfights, not early game. If you're getting bullied out by an Ori in the early game, learn to play against her.
Now, Syndra is a different story. Right now, she's pick or ban (or she should be, at least). Her AoE cc is insane, her ult is insane burst (I've killed a squishy target with 4 balls by dropping a Q and ulting, full to 0), and her damage has no downtime because of how low cd her balls are and how much they hurt, too. With Brand, Orianna, and other burst mages, their damage comes out in just that - bursts, typically requiring their ultimates. Brand can rip apart a team with his ult if they stand too close together and let him get 3 stacks of his passive on one and at least 2 stacks on everyone else - but there's soooooooo much easy counterplay to that: don't get into a giant mosh pit in teamfights and he'll have to burst people 1 at a time, and he doesn't have the ability to burst anyone without people for his R to bounce around to. Orianna's Q is pretty low cooldown, yes, but the damage on it is near insignificant for most of the game. A fed Orianna's full combo of Q W R will do probably around 3/4 of the target's health, and that's if they're a squishy ADC. From there, she's reliant on her passive basic attacks and her low cd Q to finish them off - and they'll typically kill her if they have any lifesteal at all and turn after her load is blown. Orianna isn't a burst mage, she doesn't burst people down at all - she just sets up fights for her team to go in and kill things. Brand can't burst anyone without the entire team he's trying to burst standing too close together. Last thing, Orianna's ball is a skillshot, her ultimate is on a (though brief) delay - that's long enough for you to flash/dash out of it if you have any mobility at all, and Brand is entirely reliant on his Q and W for teamfights, which are a skillshot and a delay. Neither of them are broken, at all, they both have so much counterplay to them that I just can't even fathom how bad you have to be to lose to them hard enough to complain about their balance. Brand, don't clump up when you group as 5 and run away from whoever his ult is bouncing to and he's useless. Ori has no burst at all, just teamfight setup. End rant.
and 
who are just complete slug holes of broken, but it also goes for others. Brand in any situation can kill an entire team if played well. I mean it doesn't have to be nerfs to their late game, but their early, they should not be able to just smite you out of existence. 
