Bigger is not always Better?
My biggest fear about the current state and future of LoL is it is going to get WAY too big and get impossible to balance properly. New items, champs, masteries, runes, etc, etc, there are already SO MANY things to balance out. I personally think that it has already started, and it will only get worse.
I mean, it has gotten to the point where ITEMS determine flavor of the month, not the champs themselves. One minor tweak to "this" item COMPLETELY changes the meta, etc. I have been playing since S2 (when this game was a WHOLE lot simpler) and, although I welcome change and love most of the new things Riot has implemented (in theory, at least), I think that this game is just getting too big...and it keeps growing.