What if Varus and his Sister were re-released together similarly to Morgana & Kayle?
Varus receiving the Morgana sized Update (New Visuals, Voicelines, Ability Visuals, Animations).
And his Sister well, getting released as a new Champion I suppose (Female Darkin who would be a Support or a Mage, since we have Aatrox - Top, Rhaast - Jungle, Varus - Bot. But I think it would make much more sense if she was a Support since they don't seem on bad terms considering Varus is looking for her and it would seem quite interesting if they had a Kayle and Morgana sized connection between them).
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Both having a gameplay connection to one another (similar abilities but with opposite effects) or (as one of my ideas in rough theory is her having a main Ability or Passive which would function as a double edged sword effect, where the pain that she endures she can give to her ally which would be Varus in this case, and how she would have means of surviving lots of damage hits to make this work. The idea that sparked this is her being this Darkin who has mastered of pain endurance and her weapon, which a lot of people want to be a whip can heal them).
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Both having a lot of Voice Lines when near each other, or them both having a part to speak in the same sentence (Example... Sister: We are.. Varus: forsaken.)
I don't know, for me it just sounds kinda awesome in theory.