Which build and runes? I've tested a lot. I think I'm too stubborn and go tiamat + trinity every single time. Also I found that conqueror and press the attack are too hard to proc cus Qiyana is squishy and can't spend much time in long fights. So I end up running around and poking which means electrocute or dark harvest seem to be the go to.
I like Dark Harvest on her with Taste of Blood, with Bisquits and Tonic/Approach Velocity is what is go for lane Qiyana.
Her early game is weak but with prep can guarantee kills even as is, but going for the scaling is better.
For jungle, Dark Harvest again, but Sudden Impact or Cheap Shot. I feel like it's preference and Cheap Shot feels better for an early game if your team has good laners while Sudden Impact for scaling. With secondary in Sorcery, Water Walking and Celerity.
Ravenous Hunter for both.
