the other issue with Scaling CDR Glyphs is that if you use 9, you get 15% CDR, Which means you end up with 6 (Which gives 10) and use 3 other blue Runes, or end up wasting stats.
Overall, yes, 40% CDR is nice, but most of the time it's so difficult to obtain. You have to create a specialized rune page, a specialized build path that's not 100% effective in all situations, and honestly,
20% CDR with more AP has some pros and cons vs 40/45% CDR with less AP.
20% CDR with more AP has a more potent one burst combo, while 40/45% CDR with less AP has a slightly higher DPS build. Both are usable, and in the case of Lux, both have situations in which they're preferable.