Should my Nasus lose against an irelia?

Theoretically, Nasus should lose EVERY lane matchup (unless AP), for the simple fact that he wants to stack his Q, not duke it out with the enemy laner.

AFTER laning phase, that's where Nasus shines.

Irelia has a much stronger early and mid game, where as Nasus is fully late game unless something goes insanely well early on. Just respect her power spike and continue working toward your own and you should at least go even with her.

In lane, no. Play safe, freeze lane as best as you can and farm Q. Late game now, you can obliterate her.

nasus losing to someone based off autoing attacking? Yeah.... I think you're just trash at nasus lol you literally just get any mana item and then wither her and win.

Outside of going all-in on her early? No Nasus shouldn't lose.