Add an "Incomplete Masteries" warning in champion select
I, and I'm sure many other people whether low or high rank, often encounter that time when they're editing their masteries and then have to pick/ban and forget to complete them. Or possibly just open it up, and forget to add your last 2 mastery lines and move on to the next presets.
Anyway, before the game starts during that period of waiting to trade and pick skins or whatnot, add a "Warning: Incomplete Masteries" sign at the top of the screen and maybe a "bleep" sound if their current mastery page is uncompleted. And of course make the number go down with levels for low levels who are annoyed.