Calling it now, no Ranged Champion is going to buy Wits End
They might as well make it a Melee only item because it's actually useless on Ranged champions. Only the stats of the item are somewhat considerable, as for the Passive it's just pointless (33% effective heal of flat 80 at max level), without massive amounts of AS the healing won't be noticeable.
Any ranged champion who is below half hp is almost always assured to be killed easily so the Healing that this item offers is essentially in the end not worth investing an inventory slot into.
###I'm not even sure that the "Bruisers" (that were the target of this item apparently, based on patch notes) will even find any use of this item. It's literally just a direct buff to Master Yi, Jax.
Another underrated item gone...

if you have ~350 AD for melee