[Shower Thought] What if the mastery changes are so that Riot can remove runes?
Runes give around 1k worth of stats.
Arguably masteries give more at the present time with %-based stuff (+5% damage. % of your max HP as a shield, etc)
If runes were removed, you'd still have fairly high stats/damage across the board but you wouldn't have the raw stuff from stats. Ergo the change would likely bet a net-neutral and reset the game back to a time where stuff wasn't as bad and the mastery system gave a lot less raw-statistical power than it does now.