If you are struggling vs. X Champion...
Maybe adapt your build and NOT build the same items every game nor build in the same order.
Are you facing someone with a really dangerous Debuff like
,
, or
?
-Get a
for yourself or get a
for your teammates. Staying alive deals much more damage than dying in 4 seconds.
Are you facing beefy champions like
,
, or
?
-Replace your main AD item with
or your main AP item with
. 70 extra Attack Damage or 80 extra AP on a 4000 HP target is much less than dealing 5% of its HP per hit.
Are there AA-reliant champions on the enemy team like
,
,
,
, or
?
-Cut down their DPS by building a
(don't show an act of true love with this) or return some of their damage with a
or with
. Ok? Ok.
Are you facing a mostly AP composition like
?
-Try a
to pressure a side lane or get a
to protect your teammates.
Is the enemy team getting resistances early or have naturally early resistances like
or
?
-Might need penetration early. Get that
or
earlier than usual or implement a
or
into your build so your teammates can deal more damage.
It's really annoying to see players build the same items over and over regardless of the situation. Their main excuse is that it's recommended or that it's from a MOBAFire Guide -- most of these guides even explicitly tell players to build X item for different situations. The only items that should be built every game regardless of situation are an upgraded Trinket, Boots, Jungle Items for Junglers, Sightstone for Supports, and wards. Aside from those items, think about your item build before you automatically buy a Bloodthirster when a Blade would have been better.
stacking makes my stomach turn. Herp derp, lets waste 1320G for an "early advantage". I can see why people would get a second one, sure, but after 2, I question if they trying to build
out of 5


game earlier, and I was just flat out getting my ass kicked by their entire team. My team refused to help me and were basically trolling me.
Mid:
Top: 
last game who built nothing but armor.

top
jungle
mid
bottom
vs
etc.
Best item in game. Build it.