Singed and Warwick have had a complicated relationship

Originally, Warwick was Singed's mentor, taught Singed everything he knew about chemistry. He became a werewolf during the Noxian invasion of Ionia when he and Singed were making chemical weapons for Noxus. Soraka cursed him, and he became the werewolf with an unending need for human flesh and blood. He became the blood hunter.

Then, when Riot rewrote his lore, Warwick became a hunter, a procurer of things. He was the best at it, but wanted to be better. So he had his friend Singed make him a potion. But it was short one ingredient: Soraka's Heart. He tried to get it but couldn't, yet he still drank the potion. It turned him into a werewolf, with heightened senses, but because it was incomplete, so was he. His human side slips further away every day that passes and Warwick becomes more feral, unless he can sate his thirst with Soraka's blood.

And in the newest lore, Warwick is some rando who Singed kidnaps off the street, tortures and warps with alchemistry to create a beast, a "chimeric predator"

Riot, while it is wayyyyyyyyyyyyyyyyyyyyyyyyy to early to pass judgment on the sort of character that Warwick will be, you have me disappointed at the moment. In the past, Warwick was always striving for something. He has always been my favorite character in the game, followed closely by Singed. When I heard that he was finally getting his long awaited rework, I was so excited. I could finally play my blood hunter again! The King in the Jungle had returned! But it seems to me that Warwick will go the way of Viktor and just become another written off character. He is literally a nobody, kidnapped and tested upon by Singed, who now is nothing more than a beast. An alchemical predator at that, not even a true wolf.

Warwick and Singed were friends! He was his mentor, his friend, and now he is nothing to him but a "failure [that] adds to a vast reservoir of knowledge"

Here's to old friends who are now no longer. "Shaken not Stirred"