I want to know more about the runes Ryze collects

Do they grant unique power for each rune, or is each one a power-up of the same magic that Ryze has become proficient at (if he's even using their power)?

Will we ever see a new champion who has happened upon a rune, or sought it out purposely, and acquired its immense power? Is there a champion who already has a rune and we just don't know it yet? I would like to see how that shakes things up; depending on their faction, or if it's from somewhere we don't have much representation from yet, how would they use that power?

give me story riot