Leblanc is gonna have a field day.
The changes to the game since LB has been away will cause it to favor her immensely.
Runes and Item changes are also big, but I'll just focus on the new champions.
The following champions were released after Leblanc's rework.
The following champions have received reworks since Leblanc's rework

Out of these champions, I can't see many faces that would actually do well against the new LB.
(SA)
will all get blown up by a single rotation.
(Rhaast)
will get blown up slightly less quickly, but will die nonetheless.
will be mincemeat in the early game, since he is really damn squishy until he gets items.
won't die to her, but won't be able to get her killed.
are the only new faces I can confidently say will be able to deal with her.
So many champions who have never known the terror of the Q-R double tap instagib.
So much fresh meat.
Be afraid, be very afraid.
of all champs... her rework, alongside
, were the ONLY two successful reworks in the assassin update.
were amazing, while
were made more clunky.
was successful in stopping him from building tank,
was given more room to express skill (if only as a band-aid before a larger rework), and
was made slightly less cancerous..
were wholly mediocre.
+
.