I Don't Think Vayne will be much of an issue come pre-season
The reason I say this is because of the new itemizations and the buffs to some of the adcs who used to keep her check in lane. The adcs I am referring to are cait, Lucian, and corki. Lucian isn't getting changed as much as a champion, but the new items make him down retarded (people have yet to realize this), and the same can be said of corki. And with the vayne nerfs, and the...minus 3 ad..her early game will be much more vulnerable than it once was.