[5.16 Discussion/Predictions] R.I.P. Mages; Welcome: Age of the AD Midlaners.
If you haven't seen the Magic Resist/Armor changes, as well as some of the champion changes, here are the Patch 5.16 PBE notes: http://www.surrenderat20.net/2015/08/84-pbe-update.html?m=1
Seeing as Magic Resist is being buffed and Armor is being nerfed, I feel like 5.16 is going to bring a new age of midlaners. As the title says, AD Midlaners. However, since health and health regen are being increased, the League of Tanks is also going to come back again, making assassins still a bad choice.
So, my prediction is we're going to see a lot of Riven, Yasuo, Lee Sin, Lucian, Varus, Urgot, and Wukong mid. As well, with the Lissandra buff, I feel like she'll be a pretty viable choice too to counter the AD midlaners. Vel'koz will also become a much stronger pick due to his true damage and ability to counter gapclosers with his Q and E (he's already Tier 1, I think he'll either stay Tier 1 or move to Godtier).
This is all speculation though. I'd like to see more discussion about this.