Extremely useful tip for everyone playing with Smart Cast (Quick cast)
If you are using smartcasts, disable "Replace Quick cast with Quick Cast with Indicator in the quickbind UI" option in your bind menu. This thing is TURNED ON BY DEFAULT, and adds serious INPUT LAG and gives you ability to "correct" skillshots, which means you'll be that much less accurate. This is extremely noticable on high APM/skillshot reliant champions such as
.