Would probably be broken. Simply because you can wait for it to activate, then use your ultimate or any key spell you have. A lot of champions are already balanced around what kinds of CDs they have. Every champion would have to be balanced around potentially having an extra 20% CDR from that keystone. it works somewhat with lethal temp because the champion still needs to sit there and auto each time. To make the full use out of it, you need to keep yourself in danger and basically snare yourself if you're above the AS limit. With this rune, you just have to fire a rotation of spells and you're getting a game changing effect out of it. Maybe it could work if it was something along the lines of "You're next spell has an extra 10-20%cdr. This doesn't work on ultimate spells."