There is little to no chance of coming back anymore with Cinderhulk Tank meta. RIP Assassins.
Assassin types are slowly being weeded out and swapped out for late game champs, and basically it has become whichever team gets a slight lead early and gets that HP going is going to win the game with little to no chance of coming back. Assassin meta was fun at least they had a chance to completely turn a game on its head by deleting a carry real quick in that crucial team fight. Now it's like watching Kevin Sorbo from Hercules and Russell Crowe from Gladiator having a pillow fight and waiting to see who wins.
The only real chance to have a comeback is if their team is mostly early game champs and they fall off, but if they get too far ahead you might still be in trouble.