Trying to get back into vayne...
1st and foremost... I am not asking anyone to remind me that Doublelift said vayne isnt worth playing in this meta. I know not to play her against 3 tank teams and to not pick her early. But thats ranked and I know I wont pick her unless I'm 4th/5th pick adc. But for normals I would still like to get back used to her because I'm honestly getting tired of playing jinx/kalista/graves/corki.
The way I play her now if I'm against a poke/cc heavy bot like a lucian/corki/morg/etc I generally max my Q but still rush botrk into PD into IE into Ghost Blade.
If I'm against a non poke team then I build IE into Botrk and max Q for the high damage out put.
If I'm against a tanky bot like a leona/braum/thresh and the enemy team somehow got like a sej/mumu/hec/etc jungle then I rush Botrk and max W.
What would be the best Skill max and Item build for her atm?
, 
and more attack speed. Then just adapting to the lane. More armor, mr, hp, or even damage if needed. Prefered 6 slots were usually 
then either, more survivability in something like 
, more damage with 
, or a mix like 
(But that was the old one, haven't tried the new one)