Don't tell me to burst them when these items + a support attached to their ass 
are always ready to negate all your damage. Also, throwing CC or hitting them with exhaust is difficult since Vayne can just go invisible and Twitch is melting your whole team from the other side of the planet.
Can someone explain? I keep losing to them and I'm kinda tired.
TheDesoIation2 votesIf your adc isn't good late game you might aswell go afk vayne meh low range but if you let twitch get to late game and you don't have good dive and a good scaling adc you autolose
Leaf on Bush1 votesWith a coordinated team + good timing and not a "1 by 1 we try to kill vayne and her support and then we all die and complain"-clown fiesta.
Swarovsko1 votesCoordinated team in soloq? lmao
Leaf on Bush1 votesApparently your enemies are coordinated enough to keep Vayne alive and allow her to carry so.... what's your point?
z63XnLCMwX1 votesPick 
just OK jungler1 votesPICK THEM OFF, CC THEM, BURST THEM DOWN, WARD PROPERLY, IM VERY SURE A JANNA AND TWITCH COULDNT 2 V 5, OR ELSE THEY WOULD HAVE ENDED MID GAME :)