Make Sure To Say "Screw it" Early On

I dunno, man, I had a Nid game just now where I was focused on harder than a fat dude focuses on the crab legs at the seafood buffet. There was no way I could turn the situation around by buying AP, anymore, because the enemy would always have way way way way way more money thus damage than I.

At that point where I was depressed and hopeless, I sold everything--everything--and played grabby hands with the shop's tank items. Suddenly, that team that was diving to the backlines of my team for me was getting stuck there unable to melt and back like before. Their collective thought at that point was, "Oh shit," and my team could finally bring down the hammer on those sitting ducks. Two teamfights after my build change, we went from the brink of extinction to consuming them and their nexus.

If you try and try and do not succeed, give up...

...your entire build. You will break the meta, you will be playing in a way you are unaccustomed to, but you will stand a fighting chance with a surprise bait.