The point of NS is to defend as long as possible 20 mins max, or push as hard as possible when attacking.
What I have done personally is play champs that can be built offensively AND defensive even if they are OO champs. I have found that Irella and Volibear are very good with Nexus seige.
When playing defensive get the invuln, and the turret lazer for your turret, when playing attackers buy the minion buff and the cannon. The banner is good, but the buffed minions take longer to kill and deal more damage to the turrets.
Also what ever you do DO NOT let the defenders push their minions into your port point, thus powers up the obliteration cannon, and holy cow that thing hurts.
Just some words from someone who has only played 4 games and lost none of them.