Unless I'm reading this wrong, Ultimore is a hilariously bad idea
Gain 5% cooldown reduction and maximum cooldown reduction on your ultimate. This increases by 1.5% each time you cast your ultimate. Stacks up to 10 times.
What?? The whole point of the ULTIMATE ability is that for 95% of the roster (excluding transform champs and such) it's your most powerful ability with big impact and a long cooldown to offset that. Dozens of champions are designed almost explicitly around how often their ultimate is up.
Riot will freak out and gut global ults on champs like Shen, Galio, and GP, but now introduce a keystone that lets them get their CDs on 55% of the cooldown immediately at level 6?? And then allow them to stack up to 15% more CDR for potential ultimate CD that is less than half of the base CD.
Imagine this on any number of champs that have super annoying ultimates that let them snowball a lane easily, like Zed or Fizz or Trundle or Syndra. Unless I'm somehow misreading the tooltip this is easily the most broken keystone Riot has thus unveiled. "Hur dur damage tradeoff" isn't shit. Getting 45% CDR on your ult at level 6 is just utter nonsense. There's no reason not to take this on a vast majority of the roster. It vastly improves your ability and puts an opponent without the ability at a disadvantage. Think you're cute playing Vel'Koz with Thunderlord's? Nope, Ahri has Ultimore and is using her ult every 30 seconds. This rune is a huge 'go fuck yourself' to the people that are too dumb not to take it.
Champions are fucking BALANCED around their ultimates. Think it's toxic for Malz or Vi to come into your lane and click on you for a nigh-guaranteed kill? Sucks to suck, now they do it 60% more. This is such an absurd and flawed idea and I implore Riot to not release any iteration of this nonsense.
EDIT: Yes, they clarified, its 5% initially then 10% as you stack. The rune was poorly worded and could lead to different interpretations. Thank you for clarifying Riot and others.
: "Hey, my ult is finally less than 180 seconds at max rank...... oh, it now does 20% less damage because it's too strong with this new rune... shit."

is also an interesting case, since he may be able to stack the cdr off the resets.

to be honest
's active with enough CDR, though you have a short window of time to ult them before they regain their QSS.
and 
that have very long early CDs, it'd take nearly 25 minutes of game time to get these casts in, assuming you did it right away and didn't use your ult strategically.
, some others.
can press R 4 times a single fight now. Ecksdee.