Kha'Zix and wards
Edit: okay maybe I was wrong, maybe not...about the loss of vision due to enemy wards. What I do know is that high grass protects players from Kha'Zix's isolation for some reason. I thought it didn't used to work like that so I guess I'm an idiot.
Wards can make a champion not isolated which means Kha'Zix and his team can't see them. If he catches someone all alone, all they have to do is put down a ward nearby and all of a sudden they're not isolated anymore. This not only makes it harder to tell if they are going to get reinforcements or not, but it also means that even if Kha'Zix is confident they are not being reinforced, he still can't do extra damage with his Q.
I've been finding the main way to win with Kha'Zix generally is to get the Sightstone myself and the Red trinket. Then you can kill wards so your Q does damage, but the opponent always has the ability to just slam a ward down in the middle of a skirmish and wreck your 3 second cooldown ability's damage.
What will RIot do about this? Nothing? It's been somewhat oppressive for Kha'Zix ever since they introduced the trinkets. One idea is to not let a ward count as an ally for the purposes of isolation. Another might be to add something to Kha'Zix's kit so that he doesn't have to get a sweeper or so that getting one is more attractive. Does that mean he should be able to kill wards without detecting them(for example, if you activate your ultimate and a ward is within X range while you're invisible, it expires instantly)? Or maybe detect them easier? The Raptor Smite buff can only do so much work.
There is a big difference in his effectiveness when the opponents don't know how Kha'Zix works. They don't just throw down wards to protect themselves from him, at least not in situations where it wouldn't help against any other champion. And he's able to do his job without performing all this extra preparation work. I don't mind terribly buying a different trinket but I find it annoying that I have to effectively play a 5 item slot champion if I want to pick him. Even as a support, and when I get a tier 3 gold income item, I still may sell it at late game, while Kha'Zix has to trade some Q damage for his final item...it just doesn't make sense to me.