Im pretty bad with Vlad but i know you get WotA and i think Rylais, then you build straight tank making sure to pick up a Spirit Visage at some point.
Brand is easy, EQW is a great combo, the E sets off your passive, the Q stuns off of it, and the W deals increased damage. W is for poking as it is easy to hit and has a large radius. Make sure to use your ult when there are 2-3 champs in one place, specially if they are surrounded by minions.
Annie... wait for stun flash tibbers.
Malzahar is really fun and not hard to farm with but he pushes hard so be careful. It does take some skill to fight 2 people at once since he is designed for 1v1's but in time you will know what to do. E for farming and mana sustain, Q for poke, W is a waste of mana to farm with, try to only use R when they are standing on W. Poke with Q, farm with E, hit them 2-3 times with Q and wait for E to bounce to them then throw down W and hit R, maybe ignite if needed (but be careful hitting ignite can cancel your ult). Thats my normal kill combo, it does pretty good too. Max E first, Q if they are immobile or are cast reliant, W if they are building tanky (it does %hp damage; i usually max this as hitting Q on a slightly mobile target is hard) obviously always take a point in your ult when you can.
I dont use Ryze ever.
Try Mordekaiser lol, he is really fun you just spam E, and just like Vlad he uses his health has a resource although he doesnt have a way of getting it back.
Xerath is super fun to poke with his Q.