2v2v2v2v2v2: Faction War
Summoner's Rift. Blue (bot), Green (mid) and Yellow (top). Purple (bot), red (mid) and orange (top).
Brambleback and Sentinels have a merged buff system on a different monster, giving both buffs at half the value, which can stack up to four times (if you can steal all four jungles' buffs).
Blue, green and yellow cannot hurt each other in home base, but can hurt each other outside of base. Inner towers do not hurt BGY, either. The same goes for PRO.
You can toggle friendly fire by pressing ctrl+(5-0, for each team), if you don't want to hurt your proxy buddies outside of home base.
Here is how you win/lose: if all of your lane turrets are down, you lose if your nexus is destroyed. If any of your turrets are still standing when your nexus is destroyed, you gain a victory. If the enemy nexus is destroyed, the enemy turrets in your lane must be destroyed to get the victory.
This game mode produces a very shady alliance, especially during late game. Let's say you're yellow: if the nexus is in danger, and your turrets are up, you're interested in defending your turrets, because orange will be pushing for your turrets to be destroyed for their victory. Change up your alliances (even through all chat) to become victorious. Who are your allies, anyway?
I think you can only speak to your partner through regular chat? Or with your original teammates? Or with anybody you ally with throughout (granted they ally with you to have their chat messages appear on your end).