Inevitably, given the reason you've presented in your first sentence. As for how big remains to be seen, though I suspect it won't be nearly so large that Riot would create a new gamemode for it.
My prediction is, taking into account Riot's typical modus operandi, the event will come with a new champion, some skins, and possibly a unique login distinct from any champion. Updated lores where appropriate, to a point; Riot doesn't like doing too many stories at a single time.
I sincerely doubt the event would actually explore The Void proper, since it is a very inaccessible location to pretty much everyone from Runeterra, and even the Voidborn do not seem capable of returning to it once they have left.
Keep your non-euclidean appendages crossed.