Which skins scare you the most on either team?
If the enemy team has any Swain skin, especially Northern Front, I know this is going to be more of a torture session than a game. Justicar Syndras are usually terrifying to play against.
On the flip side, Pulsefire Ezreals tend to suck, Assassin Yis tend to be most likely to rush an IE in the jungle and feed, and SKT Zeds tend to fall apart if their team doesn't perform to their MLG standards.

ultimate skin. They are either the godyr, or they are just a little bambi. No in between.
GET DUNKED BITCH
well I have 80 cs to your pitiful 30 cs
skin. I already want to afk when i see any yorick in my lane...
and if he has a skin :''''''''''(
.
Either this guy is going to start the game by taking two buffs at the same time while simultaneously ganking a lane, or he'll level his Q/E first and wonder why the jungle is so difficult.
Dark Valkyrie; no-one buys this skin for her except die-hard Diana players.
Armor of the Fifth Age skin. He will steal everything you hold dear and look absolutely dashing while doing it.
Mecha skin. They usually play really aggressive and often end up either snowballing out of control or feeding to heaven and back.
Dragon Slayer skin. They are usually very cocky (even for a Vayne) and have a higher than average tendency to rage at our support.
- You know this guy is going to pub stomp.
+ Championship
I'm in some hard times.
Any skin. An un-killable bird monster that somehow heals more damage than your team can dish out.
Noxus Poppy. She will make your skills look like poopy.
Triumphant Ryze. Don't leave your fountain. Scratch that, you CAN'T leave your fountain.
Any of the old skins. Playing this dude since his release, they will make your life hell.
Zombie Brand. I swear they all use hacks.