I hope to one day see these become reality, despite their impossibly low chances:

lee sin is not very good

sejuani is the goddess of the jungle (already happened, yes, but for like 20 minutes before she was shoved back into unviability)

draven is the god of adc's

a husband/wife or a parent/child relationship champion duo is introduced (not unlikely but i want it)

star wars reference skins for the upcoming movie (darth kassadin anyone?)

vayne is only average and not that popular

zac becomes extremely popular

baker pantheon skin